Welcome to the Tessarz Lab
Chromatin and Transcriptional Regulation in the context of Ageing
We are interested in understanding how chromatin architecture regulates transcription. We study this on a mechanistic level, but are becoming more and more fascinated by the question how physiological alterations impinge on chromatin and thus, transcription. In particular, we are interested in the role of metabolism and/or ageing. To address this, we make use of model organisms and in vitro culture of somatic stem cells and organoid systems. We combine this with biochemistry, cell biology and NGS-based approaches. To learn more about the linked research directions in the lab, please follow the links below.